pentobarbital will decrease the level or impact of parecoxib by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Watch.
pentobarbital will reduce the extent or result of oxybutynin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will decrease the extent or impact of sulfamethoxazole by influencing hepatic enzyme CYP2C9/10 metabolism. Minimal/Significance Not known.
pentobarbital will lower the extent or effect of quinidine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
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Induction of microsomal enzymes by this drug, may shorten the half-life of doxycycline for as long as 2 weeks right after barbiturate therapy discontinued; check medical reaction to doxycycline carefully if the two medicine administered concurrently
pentobarbital will decrease the extent or influence of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Powerful CYP3A4 inducers are anticipated to lead to considerable decreases in sildenafil plasma ranges
Contraindicated (1)pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust check here CYP3A4 inducers can minimize panobinostat concentrations by ~70% and lead to cure failure.
pentobarbital will decrease the extent or outcome of cinacalcet by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
pentobarbital will lower the level or result of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unidentified.
pentobarbital will minimize the level or influence of dexamethasone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Contraindicated (1)pentobarbital will lessen the level or influence of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
fentanyl intranasal and pentobarbital both of those enhance sedation. Steer clear of or Use Alternate Drug. Restrict use to patients for whom choice therapy solutions are insufficient
Should the buprenorphine dose is insufficient as well as CYP3A4 inducer can not be lessened or discontinued, changeover the client again to the buprenorphine formulation that allows dose changes.